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Biodegradable nano-micro carrier systems for sustained pulmonary drug delivery: (I) Self-assembled nanoparticles encapsulated in respirable/swellable semi-IPN microspheres

Design of appropriate inhaled carriers with adequate aerodynamic properties, drug release, biodegradation and evasion of macrophage uptake is a major challenge for controlled release pulmonary drug delivery. In this study, PEG graft copolymerized onto N-phthaloyl chitosan (NPHCs) was synthesized the...

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Autori principali: El-Sherbiny, I. M., Smyth, H. D. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654806/
https://ncbi.nlm.nih.gov/pubmed/20580794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.05.032
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