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A solid-phase CuAAC strategy for the synthesis of PNA containing nucleobase surrogates
The synthesis of an azide containing PNA monomer is described. The monomer was incorporated into two PNA sequences for the purpose of synthesizing an intercalating fluorophore-labeled PNA and a metal binding hairpin using a solid phase copper catalyzed azide-alkyne Huisgen cycloaddition (CuAAC). Cli...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654728/ https://ncbi.nlm.nih.gov/pubmed/23422048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.23982 |
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