Functional characterization of a STAT3-dependent dendritic cell-derived CD14(+) cell population arising upon IL-10-driven maturation

Interleukin (IL)-10 is a major cancer-related immunosuppressive factor, exhibiting a unique ability to hamper the maturation of dendritic cells (DCs). We have previously reported that IL-10 induces the conversion of activated, migratory CD1a(+) DCs found in the human skin to CD14(+)CD141(+) macropha...

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Detalhes bibliográficos
Main Authors: Lindenberg, Jelle J., van de Ven, Rieneke, Lougheed, Sinéad M., Zomer, Anoek, Santegoets, Saskia J.A.M., Griffioen, Arjan W., Hooijberg, Erik, van den Eertwegh, Alfons J.M., Thijssen, Victor L., Scheper, Rik J., Oosterhoff, Dinja, de Gruijl, Tanja D.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654600/
https://ncbi.nlm.nih.gov/pubmed/23734330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23837
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