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Aberrant expression of costimulatory molecules in splenocytes of the mevalonate kinase-deficient mouse model of human hyper-IgD syndrome (HIDS)

OBJECTIVE: We sought to determine the activation status and proliferative capacities of splenic lymphocyte populations from a mevalonate kinase-deficient mouse model of hyper-IgD syndrome (HIDS). We previously reported that murine mevalonate kinase gene ablation was embryonic lethal for homozygous m...

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Auteurs principaux: Hager, Elizabeth J., Piganelli, Jon D., Tse, Hubert M., Gibson, K. Michael
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654530/
https://ncbi.nlm.nih.gov/pubmed/21607759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-011-9349-x
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