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Fusion Activity of HIV gp41 Fusion Domain is Related to its Secondary Structure and Depth of Membrane Insertion in a Cholesterol-Dependent Fashion

The HIV gp41 fusion domain plays a critical role in membrane fusion during viral entry. A thorough understanding of the relationship between the structure and activity of the fusion domain in different lipid environments helps to formulate mechanistic models on how it might function in mediating mem...

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Autori principali: Lai, Alex L., Moorthy, Anna Eswara, Li, Yinling, Tamm, Lukas K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654243/
https://ncbi.nlm.nih.gov/pubmed/22343048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.02.010
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