Benzo[a]pyrene decreases global and gene specific DNA methylation during zebrafish development

DNA methylation is important for gene regulation and is vulnerable to early-life exposure to environmental contaminants. We found that direct waterborne benzo[a]pyrene (BaP) exposure at 24 μg/L from 2.5 to 96 hours post fertilization (hpf) to zebrafish embryos significantly decreased global cytosine...

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Main Authors: Fang, Xiefan, Thornton, Cammi, Scheffler, Brian E., Willett, Kristine L.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654064/
https://ncbi.nlm.nih.gov/pubmed/23542452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.etap.2013.02.014
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