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What role (if any) does the highly conserved CSB-PGBD3 fusion protein play in Cockayne syndrome?
The PGBD3 piggyBac transposon inserted into CSB intron 5 early in the primate lineage. As a result of alternative splicing, the human CSB gene now encodes three proteins: CSB, a CSB-PGBD3 fusion protein that joins the N-terminal CSB domain to the C-terminal PGBD3 transposase domain, and PGBD3 transp...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654029/ https://ncbi.nlm.nih.gov/pubmed/23369858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2013.01.001 |
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