PSMs of Hypervirulent Staphylococcus aureus Act as Intracellular Toxins That Kill Infected Osteoblasts

Epidemic community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is associated with more severe and acute forms of osteomyelitis than healthcare-associated (HA-) MRSA. Although S. aureus is now recognized as a facultative intracellular pathogen, the contribution of osteoblast invasi...

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Auteurs principaux: Rasigade, Jean-Philippe, Trouillet-Assant, Sophie, Ferry, Tristan, Diep, Binh An, Sapin, Anaïs, Lhoste, Yannick, Ranfaing, Jérémy, Badiou, Cédric, Benito, Yvonne, Bes, Michèle, Couzon, Florence, Tigaud, Sylvestre, Lina, Gérard, Etienne, Jérôme, Vandenesch, François, Laurent, Frédéric
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653922/
https://ncbi.nlm.nih.gov/pubmed/23690994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063176
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