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Utility of Experimental Design in Pre-Column Derivatization for the Analysis of Tobramycin by HPLC—Fluorescence Detection: Application to Ophthalmic Solution and Human Plasma
A novel, selective, and sensitive reversed phase high-performance liquid chromatography (HPLC) method coupled with fluorescence detection has been developed for the determination of tobramycin (TOB) in pure form, in ophthalmic solution and in spiked human plasma. Since TOB lacks UV absorbing chromop...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Libertas Academica
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653852/ https://ncbi.nlm.nih.gov/pubmed/23700362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/ACI.S11612 |
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