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Repressors NFI and NFY participate in organ-specific regulation of VWF promoter activity in transgenic mice

OBJECTIVE: To determine the role of repressors in cell type and organ-specific activation of von Willebrand factor (VWF) promoter sequences −487 to +247 in vivo. METHODS AND RESULTS: Activation patterns of wild-type and mutant VWF promoters (sequences −487 to +247) containing mutations in repressors...

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Detalhes bibliográficos
Main Authors: Nassiri, Marjan, Liu, Ju, Kulak, Stephen, Uwiera, Richard R.E., Aird, William C., Ballermann, Barbara J., Jahroudi, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653838/
https://ncbi.nlm.nih.gov/pubmed/20431063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.206680
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