The Drosophila Homologue of the Amyloid Precursor Protein Is a Conserved Modulator of Wnt PCP Signaling

Wnt Planar Cell Polarity (PCP) signaling is a universal regulator of polarity in epithelial cells, but it regulates axon outgrowth in neurons, suggesting the existence of axonal modulators of Wnt-PCP activity. The Amyloid precursor proteins (APPs) are intensely investigated because of their link to...

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Detalhes bibliográficos
Main Authors: Soldano, Alessia, Okray, Zeynep, Janovska, Pavlina, Tmejová, Kateřina, Reynaud, Elodie, Claeys, Annelies, Yan, Jiekun, Atak, Zeynep Kalender, De Strooper, Bart, Dura, Jean-Maurice, Bryja, Vítězslav, Hassan, Bassem A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653798/
https://ncbi.nlm.nih.gov/pubmed/23690751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001562
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