Expression of transfected mutant beta-actin genes: transitions toward the stable tumorigenic state.

Mutant human beta-actin genes were introduced into normal human (KD) fibroblasts and the derivative cell line HuT-12, which is immortalized but nontumorigenic, to test their ability to promote conversion to the tumorigenic state. Transfected substrains of HuT-12 fibroblasts that expressed abundant l...

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Main Authors: Leavitt, J, Ng, S Y, Varma, M, Latter, G, Burbeck, S, Gunning, P, Kedes, L
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC365379/
https://ncbi.nlm.nih.gov/pubmed/3614199
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