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Expression of transfected mutant beta-actin genes: alterations of cell morphology and evidence for autoregulation in actin pools.

Two different mutant human beta-actin genes have been introduced into normal diploid human (KD) fibroblasts and their immortalized derivative cell line, HuT-12, to assess the impact of an abnormal cytoskeletal protein on cellular phenotypes such as morphology, growth characteristics, and properties...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Leavitt, J, Ng, S Y, Aebi, U, Varma, M, Latter, G, Burbeck, S, Kedes, L, Gunning, P
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365378/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3614198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.7.2457-2466.1987
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