Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes.

NIH 3T3 cells cotransfected with the human c-fms proto-oncogene together with a 1.6-kilobase cDNA clone encoding a 256-amino-acid precursor of the human mononuclear phagocyte colony-stimulating factor CSF-1 (M-CSF) undergo transformation by an autocrine mechanism. The number of CSF-1 receptors on th...

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Опубликовано в::	Mol Cell Biol
Главные авторы:	Rettenmier, C W, Roussel, M F, Ashmun, R A, Ralph, P, Price, K, Sherr, C J
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1987
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3039346/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.7.2378-2387.1987
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