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Cancer treatment as a game: integrating evolutionary game theory into the optimal control of chemotherapy

Chemotherapy for metastatic cancer commonly fails due to evolution of drug resistance in tumor cells. Here, we view cancer treatment as a game in which the oncologists choose a therapy and tumors “choose” an adaptive strategy. We propose the oncologist can gain an upper hand in the game by choosing...

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Detaylı Bibliyografya
Asıl Yazarlar: Orlando, Paul A., Gatenby, Robert A., Brown, Joel S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653600/
https://ncbi.nlm.nih.gov/pubmed/23197192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/9/6/065007
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