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Cancer treatment as a game: integrating evolutionary game theory into the optimal control of chemotherapy
Chemotherapy for metastatic cancer commonly fails due to evolution of drug resistance in tumor cells. Here, we view cancer treatment as a game in which the oncologists choose a therapy and tumors “choose” an adaptive strategy. We propose the oncologist can gain an upper hand in the game by choosing...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653600/ https://ncbi.nlm.nih.gov/pubmed/23197192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/9/6/065007 |
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