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The dual phosphatase activity of Synaptojanin1 is required for both efficient synaptic vesicle internalization and re-availability at nerve terminals

Phosphoinositides have been implicated in synaptic vesicle recycling largely based on studies of enzymes that regulate phosphoinositide synthesis and hydrolysis. One such enzyme is Synaptojanin1, a multifunctional protein conserved from yeast to humans, which contains two phospho-inositol phosphatas...

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Detalhes bibliográficos
Main Authors: Mani, Meera, Lee, Sang Yoon, Lucast, Louise, Cremona, Ottavio, Di Paolo, Gilbert, De Camilli, Pietro, Ryan, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653591/
https://ncbi.nlm.nih.gov/pubmed/18093523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.10.032
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