Three Drosophila beta-tubulin sequences: a developmentally regulated isoform (beta 3), the testis-specific isoform (beta 2), and an assembly-defective mutation of the testis-specific isoform (B2t8) reveal both an ancient divergence in metazoan isotypes and structural constraints for beta-tubulin function.

The genomic DNA sequence and deduced amino acid sequence are presented for three Drosophila melanogaster beta-tubulins: a developmentally regulated isoform beta 3-tubulin, the wild-type testis-specific isoform beta 2-tubulin, and an ethyl methanesulfonate-induced assembly-defective mutation of the t...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Rudolph, J E, Kimble, M, Hoyle, H D, Subler, M A, Raff, E C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365347/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.6.2231-2242.1987
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