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The highly conserved U small nuclear RNA 3'-end formation signal is quite tolerant to mutation.

Formation of the 3' end of U1 and U2 small nuclear RNA (snRNA) precursors is directed by a conserved sequence called the 3' box located 9 to 28 nucleotides downstream of all metazoan U1 to U4 snRNA genes sequenced so far. Deletion of part or all of the 3' box from human U1 and U2 gene...

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Dettagli Bibliografici
Autori principali: Ach, R A, Weiner, A M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC365327/
https://ncbi.nlm.nih.gov/pubmed/3037343
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