Collagen-specific peptide conjugated high density lipoprotein nanoparticles as MR contrast agents to evaluate compositional changes in murine atherosclerotic plaques under regression conditions

OBJECTIVE: In this study, we developed magnetic resonance (MR) contrast agents based on high-density lipoprotein (HDL) nanoparticles to non-invasively visualize intraplaque macrophages and collagen content in mouse atherosclerotic plaques. BACKGROUND: Macrophages and collagen are important intraplaq...

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Détails bibliographiques
Auteurs principaux: Chen, Wei, Cormode, David P., Vengrenyuk, Yuliya, Herranz, Beatriz, Feig, Jonathan E, Klink, Ahmed, Mulder, Willem J. M., Fisher, Edward A., Fayad, Zahi A.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653172/
https://ncbi.nlm.nih.gov/pubmed/23433925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmg.2012.06.016
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