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Chromatin structure of the HLA-DR alpha gene in different functional states of major histocompatibility complex class II gene expression.

We utilized DNase I hypersensitivity mapping to study chromatin structure within the HLA-DR alpha gene. We found a single DNase I-hypersensitive site coinciding with the HLA-DR alpha gene promoter in all cells studied. Moreover, in cells that constitutively express HLA-DR, two additional DNase I-hyp...

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Publicat a:Mol Cell Biol
Autors principals: Peterlin, B M, Hardy, K J, Larsen, A S
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1987
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365303/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3600654/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.5.1967-1972.1987
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