Gamma rays and bleomycin nick DNA and reverse the DNase I sensitivity of beta-globin gene chromatin in vivo.
The active beta-globin genes in chicken erythrocytes, like all active genes, reside in large chromatin domains which are preferentially sensitive to digestion by DNase I. We have recently proposed that the special structure of chromatin in active domains is maintained by torsional stress in the DNA...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1987
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2439900/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.5.1917-1924.1987 |
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