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Targeted disruption of glutathione peroxidase 4 (GPx4) in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2

Selenoproteins are essential molecules for the mammalian antioxidant network. We previously demonstrated that targeted loss of all selenoproteins in mouse epidermis disrupted skin and hair development and caused premature death. In the current study we targeted specific selenoproteins for epidermal...

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Main Authors: Sengupta, Aniruddha, Lichti, Ulrike F., Carlson, Bradley A., Cataisson, Christophe, Ryscavage, Andrew O., Mikulec, Carol, Conrad, Marcus, Fischer, Susan M., Hatfield, Dolph L., Yuspa, Stuart H.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652900/
https://ncbi.nlm.nih.gov/pubmed/23364477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.52
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