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Selective Homocysteine Lowering Gene Transfer Improves Infarct Healing, Attenuates Remodelling, and Enhances Diastolic Function after Myocardial Infarction in Mice

BACKGROUND AND AIMS: Homocysteine levels predict heart failure incidence in prospective epidemiological studies and correlate with severity of heart failure in cross-sectional surveys. The objective of this study was to evaluate whether a selective homocysteine lowering intervention beneficially aff...

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Autors principals: Muthuramu, Ilayaraja, Jacobs, Frank, Singh, Neha, Gordts, Stephanie C., De Geest, Bart
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652839/
https://ncbi.nlm.nih.gov/pubmed/23675503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063710
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