Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity

Synapsin I (SynI) is a synaptic vesicle (SV) phosphoprotein playing multiple roles in synaptic transmission and plasticity by differentially affecting crucial steps of SV trafficking in excitatory and inhibitory synapses. SynI knockout (KO) mice are epileptic, and nonsense and missense mutations in...

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Detalhes bibliográficos
Main Authors: Lignani, Gabriele, Raimondi, Andrea, Ferrea, Enrico, Rocchi, Anna, Paonessa, Francesco, Cesca, Fabrizia, Orlando, Marta, Tkatch, Tatiana, Valtorta, Flavia, Cossette, Patrick, Baldelli, Pietro, Benfenati, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652419/
https://ncbi.nlm.nih.gov/pubmed/23406870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt071
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