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Unstable and stable CAD gene amplification: importance of flanking sequences and nuclear environment in gene amplification.

We analyzed the amplification of the CAD gene in independently isolated N-(phosphonacetyl)-L-aspartate-resistant clones derived from single parental clones in two mouse cell lines. We report for the first time that the CAD gene is amplified unstably in mouse cells, that the degree of instability var...

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Publicat a:Mol Cell Biol
Autors principals: Meinkoth, J, Killary, A M, Fournier, R E, Wahl, G M
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1987
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365229/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3600632/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.4.1415
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