Calorie restriction attenuates astrogliosis but not amyloid plaque load in aged rhesus macaques: a preliminary quantitative imaging study

While moderate calorie restriction (CR) in the absence of malnutrition has been consistently shown to have a systemic, beneficial effect against aging in several animals models, its effect on the brain microstructure in a non-human primate model remains to be studied using post-mortem histopathologi...

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Main Authors: Sridharan, Aadhavi, Pehar, Mariana, Salamat, M Shahriar, Pugh, Thomas D, Bendlin, Barbara B, Willette, Auriel A, Anderson, Rozalyn M, Kemnitz, Joseph W, Colman, Ricki J, Weindruch, Richard H, Puglielli, Luigi, Johnson, Sterling C
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652278/
https://ncbi.nlm.nih.gov/pubmed/23473840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.02.046
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