Calorie Restriction Reduces the Influence of Glucoregulatory Dysfunction on Regional Brain Volume in Aged Rhesus Monkeys

Insulin signaling dysregulation is related to neural atrophy in hippocampus and other areas affected by neurovascular and neurodegenerative disorders. It is not known if long-term calorie restriction (CR) can ameliorate this relationship through improved insulin signaling or if such an effect might...

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Autori principali: Willette, Auriel A., Bendlin, Barbara B., Colman, Ricki J., Kastman, Erik K., Field, Aaron S., Alexander, Andrew L., Sridharan, Aadhavi, Allison, David B., Anderson, Rozalyn, Voytko, Mary-Lou, Kemnitz, Joseph W., Weindruch, Richard H., Johnson, Sterling C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2012
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331743/
https://ncbi.nlm.nih.gov/pubmed/22415875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1187
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