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In Vivo Assessment of Neurodegeneration in Niemann-Pick Type C Mice by Quantitative T2 Mapping and Diffusion Tensor Imaging

PURPOSE: To quantitatively and non-invasively assess neurological disease progression in a mouse model of Niemann-Pick type C (NPC) disease by measuring white matter status with MRI techniques of T2 mapping and Diffusion Tensor Imaging (DTI). MATERIALS AND METHODS: Quantitative T2 and DTI experiment...

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Detalhes bibliográficos
Main Authors: Totenhagen, John W., Lope-Piedrafita, Silvia, Borbon, Ivan A., Yoshimaru, Eriko S., Erickson, Robert P., Trouard, Theodore P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652272/
https://ncbi.nlm.nih.gov/pubmed/22045516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmri.22837
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