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Biological Insights into Therapeutic Protein Modifications throughout Trafficking and Their Biopharmaceutical Applications

Over the lifespan of therapeutic proteins, from the point of biosynthesis to the complete clearance from tested subjects, they undergo various biological modifications. Therapeutic influences and molecular mechanisms of these modifications have been well appreciated for some while remained less unde...

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Detalhes bibliográficos
Main Authors: Zhong, Xiaotian, Wright, Jill F.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652174/
https://ncbi.nlm.nih.gov/pubmed/23690780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/273086
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