Hypoxic depression of PKG-mediated inhibition of serotonergic contraction in ovine carotid arteries

Chronic hypoxia attenuates soluble guanylate cyclase-induced vasorelaxation in serotonin (5-HT)-contracted ovine carotid arteries. Because protein kinase G (PKG) mediates many effects of soluble guanylate cyclase activation through phosphorylation of multiple kinase targets in vascular smooth muscle...

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Библиографические подробности
Главные авторы: Thorpe, Richard B., Stockman, Sara L., Williams, James M., Lincoln, Thomas M., Pearce, William J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
Предметы:
Cardiovascular and Renal Integration
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652078/
https://ncbi.nlm.nih.gov/pubmed/23447135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00212.2012
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