Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling

BACKGROUND: The Odontogenic Ameloblast-associated Protein (ODAM) is expressed in a wide range of normal epithelial, and neoplastic tissues, and we have posited that ODAM serves as a novel prognostic biomarker for breast cancer and melanoma. Transfection of ODAM into breast cancer cells yields suppre...

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Detalhes bibliográficos
Main Authors: Foster, James S, Fish, Lindsay M, Phipps, Jonathan E, Bruker, Charles T, Lewis, James M, Bell, John L, Solomon, Alan, Kestler, Daniel P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651709/
https://ncbi.nlm.nih.gov/pubmed/23648148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-227
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