miR-29c is downregulated in renal interstitial fibrosis in humans and rats and restored by HIF-α activation

Treatment with l-mimosine, which activates hypoxia-inducible factor-α (HIF-α), attenuates renal tubulointerstitial injury and improves renal function in a rat remnant kidney model. The miR-29 family of microRNAs directly targets a large number of extracellular matrix genes and reduces renal intersti...

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Detaylı Bibliyografya
Asıl Yazarlar: Fang, Yi, Yu, Xiaofang, Liu, Yong, Kriegel, Alison J., Heng, Yanyan, Xu, Xialian, Liang, Mingyu, Ding, Xiaoqiang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2013
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651624/
https://ncbi.nlm.nih.gov/pubmed/23467423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00287.2012
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