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Sex steroid hormones regulate constitutive expression of Cyp2e1 in female mouse liver

CYP2E1 is of paramount toxicological significance because it metabolically activates a large number of low-molecular-weight toxicants and carcinogens. In this context, factors that interfere with Cyp2e1 regulation may critically affect xenobiotic toxicity and carcinogenicity. The aim of this study w...

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Autori principali: Konstandi, Maria, Cheng, Jie, Gonzalez, Frank J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651618/
https://ncbi.nlm.nih.gov/pubmed/23548611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00585.2012
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