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Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner

Compounds that delay aging in model organisms may be of significant interest to anti-aging medicine, since these substances potentially provide pharmaceutical approaches to promote healthy lifespan in humans. We here aimed to test whether pharmaceutical concentrations of three fibrates, pharmacologi...

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Autors principals: Brandstädt, Sven, Schmeisser, Kathrin, Zarse, Kim, Ristow, Michael
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651519/
https://ncbi.nlm.nih.gov/pubmed/23603800
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