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Deficiency of Insulin-Like Growth Factor-1 Receptor Confers Resistance to Oxidative Stress in C2C12 Myoblasts
IGF-1 receptor (IGF-1R) signaling regulates cell growth, transformation and survival. Haploinsufficiency of the IGF-1R is reported to paradoxically confer resistance to oxidative stress in vivo and in cells cultured from Igf1r(+/−) mice. In order to determine whether IGF-1R deficiency directly confe...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651254/ https://ncbi.nlm.nih.gov/pubmed/23675509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063838 |
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