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Induction of clonal monocyte-macrophage tumors in vivo by a mouse c-myc retrovirus: rearrangement of the CSF-1 gene as a secondary transforming event.

A mouse retrovirus containing the c-myc oncogene was found to induce tumors of mononuclear phagocytic cells in vivo. All tumors expressed the c-myc retroviral gene but not the endogenous c-myc gene (with one exception), and virtually all tumors were clonal with a unique proviral integration. This ob...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Baumbach, W R, Stanley, E R, Cole, M D
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365122/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3547079/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.2.664-671.1987
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