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Soluble Guanylyl Cyclase Is Reduced in Airway Smooth Muscle Cells From a Murine Model of Allergic Asthma

Airway remodeling plays an important role in the development of airway hyperresponsiveness in asthma. Muscarinic agonists such as carbamylcholine increased cyclic GMP (cGMP) levels in bovine tracheal smooth muscle strips, via stimulation of NO-sensitive soluble guanylylcyclase (NO-sGC), which is an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Placeres-Uray, Fabiola, de Alfonzo, Ramona González, de Becemberg, Itala Lippo, Alfonzo, Marcelo J
Format: Artigo
Sprache:Inglês
Veröffentlicht: World Allergy Organization 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651105/
https://ncbi.nlm.nih.gov/pubmed/23282985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WOX.0b013e318201d80b
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