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Erythrocytic Pyruvate Kinase Mutations Causing Hemolytic Anemia, Osteosclerosis, and Secondary Hemochromatosis in Dogs

BACKGROUND: Erythrocytic pyruvate kinase (PK) deficiency, first documented in Basenjis, is the most common inherited erythroenzymopathy in dogs. OBJECTIVES: To report 3 new breed-specific PK-LR gene mutations and a retrospective survey of PK mutations in a small and selected group of Beagles and Wes...

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Detalhes bibliográficos
Main Authors: Gultekin, G. Inal, Raj, K., Foureman, P., Lehman, S., Manhart, K., Abdulmalik, O., Giger, U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650904/
https://ncbi.nlm.nih.gov/pubmed/22805166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1939-1676.2012.00958.x
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