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The viral Ki-ras gene must be expressed in the G2 phase if ts Kirsten sarcoma virus-infected NRK cells are to proliferate in serum-free medium.

NRK cells infected with a temperature-sensitive Kirsten sarcoma virus (ts371 KSV) are transformed at 36 degrees C, but are untransformed at 41 degrees C which inactivates the abnormally thermolabile oncogenic p21Ki product of the viral Ki-ras gene. At 41 degrees C, tsKSV-infected NRK cells were arre...

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Autors principals: Durkin, J P, Whitfield, J F
Format: Artigo
Idioma:Inglês
Publicat: 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC365087/
https://ncbi.nlm.nih.gov/pubmed/3031473
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