Oncogenic CUL4A determines the response to thalidomide treatment in prostate cancer

Thalidomide is experimentally used to treat various human cancers; however, clinical responses to thalidomide are sporadic. Here we demonstrate that CUL4A plays an oncogenic role in prostate cancer development and prostate cancer cells with higher level of CUL4A are particularly sensitive to thalido...

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Detalhes bibliográficos
Main Authors: Ren, Shancheng, Xu, Chuanliang, Cui, Zilian, Yu, Yongwei, Xu, Weidong, Wang, Fubo, Lu, Ji, Wei, Min, Lu, Xin, Gao, Xu, Liang, You, Mao, Jian-Hua, Sun, Yinghao
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650856/
https://ncbi.nlm.nih.gov/pubmed/22422151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-012-0885-0
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