Oncogenic CUL4A determines the response to thalidomide treatment in prostate cancer

Thalidomide is experimentally used to treat various human cancers; however, clinical responses to thalidomide are sporadic. Here we demonstrate that CUL4A plays an oncogenic role in prostate cancer development and prostate cancer cells with higher level of CUL4A are particularly sensitive to thalido...

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Autori principali: Ren, Shancheng, Xu, Chuanliang, Cui, Zilian, Yu, Yongwei, Xu, Weidong, Wang, Fubo, Lu, Ji, Wei, Min, Lu, Xin, Gao, Xu, Liang, You, Mao, Jian-Hua, Sun, Yinghao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650856/
https://ncbi.nlm.nih.gov/pubmed/22422151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-012-0885-0
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