Differential effects of norUDCA and UDCA in obstructive cholestasis in mice

BACKGROUND & AIMS: The quest for effective drugs to treat cholangiopathies led to the development of norUDCA previously shown to have potent choleretic effects and to heal cholangiopathy in Abcb4 knockout (Abcb4(−/−)) mice. Its mother compound UDCA had detrimental effects in common bile duct lig...

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Hlavní autoři: Fickert, Peter, Pollheimer, Marion J., Silbert, Dagmar, Moustafa, Tarek, Halilbasic, Emina, Krones, Elisabeth, Durchschein, Franziska, Thüringer, Andrea, Zollner, Gernot, Denk, Helmut, Trauner, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650580/
https://ncbi.nlm.nih.gov/pubmed/23369794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.01.026
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