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AGG Interruptions in (CGG)(n) DNA Repeat Tracts Modulate the Structure and Thermodynamics of Non-B Conformations in vitro()
The trinucleotide repeat sequence CGG/CCG is known to expand in the human genome. This expansion is the primary pathogenic signature of fragile X syndrome, which is the most common form of inherited mental retardation. It has been proposed that formation of non-B conformations by the repetitive sequ...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3650493/ https://ncbi.nlm.nih.gov/pubmed/20695523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1007782 |
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