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Optogenetic Modulation of an Adenylate Cyclase in Toxoplasma gondii Demonstrates a Requirement of the Parasite cAMP for Host-Cell Invasion and Stage Differentiation

Successful infection and transmission of the obligate intracellular parasite Toxoplasma gondii depends on its ability to switch between fast-replicating tachyzoite (acute) and quiescent bradyzoite (chronic) stages. Induction of cAMP in the parasitized host cells has been proposed to influence parasi...

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Detalhes bibliográficos
Main Authors: Hartmann, Anne, Arroyo-Olarte, Ruben Dario, Imkeller, Katharina, Hegemann, Peter, Lucius, Richard, Gupta, Nishith
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650408/
https://ncbi.nlm.nih.gov/pubmed/23525100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.465583
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