Mechanism of an ATP-independent Protein Disaggregase: I. STRUCTURE OF A MEMBRANE PROTEIN AGGREGATE REVEALS A MECHANISM OF RECOGNITION BY ITS CHAPERONE

Protein aggregation is detrimental to the maintenance of proper protein homeostasis in all cells. To overcome this problem, cells have evolved a network of molecular chaperones to prevent protein aggregation and even reverse existing protein aggregates. The most extensively studied disaggregase syst...

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Detalhes bibliográficos
Main Authors: Nguyen, Thang X., Jaru-Ampornpan, Peera, Lam, Vinh Q., Cao, Peigen, Piszkiewicz, Samantha, Hess, Sonja, Shan, Shu-ou
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650380/
https://ncbi.nlm.nih.gov/pubmed/23525109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.462812
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