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The Signal Peptide of the Tumor-shared Antigen Midkine Hosts CD4(+) T Cell Epitopes

Because of the key role of CD4 T cell response in immunity to tumors, we investigated the CD4(+) T cell response to the recently identified tumor antigen Midkine (MDK). By weekly stimulations of T lymphocytes harvested from seven HLA-DR-typed healthy donors, we derived CD4(+) T cell lines specific f...

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Detalhes bibliográficos
Main Authors: Kerzerho, Jerome, Schneider, Aurélie, Favry, Emmanuel, Castelli, Florence Anne, Maillère, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650375/
https://ncbi.nlm.nih.gov/pubmed/23553629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.427302
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