A highly conserved endonuclease activity present in Escherichia coli, bovine, and human cells recognizes oxidative DNA damage at sites of pyrimidines.

We have compared the sites of nucleotide incision on DNA damaged by oxidizing agents when cleavage is mediated by either Escherichia coli endonuclease III or an endonuclease present in bovine and human cells. E. coli endonuclease III, the bovine endonuclease isolated from calf thymus, and the human...

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Autores principales: Doetsch, P W, Henner, W D, Cunningham, R P, Toney, J H, Helland, D E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC365037/
https://ncbi.nlm.nih.gov/pubmed/3031465
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