Argonaute2 Regulates the Pancreatic β-Cell Secretome

Argonaute2 (Ago2) is an established component of the microRNA-induced silencing complex. Similar to miR-375 loss-of-function studies, inhibition of Ago2 in the pancreatic β-cell resulted in enhanced insulin release underlining the relationship between these two genes. Moreover, as the most abundant...

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Autori principali: Tattikota, Sudhir G., Sury, Matthias D., Rathjen, Thomas, Wessels, Hans-Hermann, Pandey, Amit K., You, Xintian, Becker, Clinton, Chen, Wei, Selbach, Matthias, Poy, Matthew N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650333/
https://ncbi.nlm.nih.gov/pubmed/23358505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.024786
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