Dose-dependent Toxicity of Humanized Renilla reniformis GFP (hrGFP) Limits Its Utility as a Reporter Gene in Mouse Muscle

Gene therapy has historically focused on delivering protein-coding genes to target cells or tissues using a variety of vectors. In recent years, the field has expanded to include gene-silencing strategies involving delivery of noncoding inhibitory RNAs, such as short hairpin RNAs or microRNAs (miRNA...

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Detalhes bibliográficos
Main Authors: Wallace, Lindsay M, Moreo, Andrew, Clark, K Reed, Harper, Scott Q
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Methods - Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650248/
https://ncbi.nlm.nih.gov/pubmed/23591809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.16
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