RANGE: Gene Transfer of Reversibly Controlled Polycistronic Genes

We developed a single vector recombinant adeno-associated viral (rAAV) expression system for spatial and reversible control of polycistronic gene expression. Our approach (i) integrates the advantages of the tetracycline (Tet)-controlled transcriptional silencer tTS(Kid) and the self-cleaving 2A pep...

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Detalhes bibliográficos
Main Authors: Chen, Yiwei, Cao, Liji, Luo, Chonglin, Ditzel, Désirée AW, Peter, Jörg, Sprengel, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Methods - Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650247/
https://ncbi.nlm.nih.gov/pubmed/23571608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.15
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