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Chronic IL9 and IL-13 Exposure Leads to an Altered Differentiation of Ciliated Cells in a Well-Differentiated Paediatric Bronchial Epithelial Cell Model

Asthma is a chronic inflammatory disease characterised by airways remodelling. In mouse models IL-9 and IL-13 have been implicated in airways remodelling including mucus hypersecretion and goblet cell hyperplasia. Their role, especially that of IL-9, has been much less studied in authentic human ex...

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Detalhes bibliográficos
Main Authors: Parker, Jeremy C., Thavagnanam, Surendran, Skibinski, Grzegorz, Lyons, Jeremy, Bell, Jennifer, Heaney, Liam G., Shields, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650011/
https://ncbi.nlm.nih.gov/pubmed/23671562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061023
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